Cholesterol Meds May Not Help Ward Off Dementia
https://ift.tt/2VsVfjt WEDNESDAY, Feb. 27, 2019 (HealthDay News) -- While effective at cutting heart risks, blood pressure and cholesterol drugs may not help preserve seniors' brain health, new research finds. That conclusion came from the tracking of more than 1,600 men and women in 21 countries. Over an average span of nearly six years, all of the seniors took different combinations of drugs to lower blood pressure and/or statins to control high cholesterol. All took memory and thinking tests at the start and end of the study, the Canadian researchers said. The result: None of the drugs appeared to have any impact on long-term mental declines. Study author Jackie Bosch said her team was not really surprised by the findings. She is an investigator at the Population Health Research Institute and an associate professor in the School of Rehabilitation Science at McMaster University in Hamilton, Ontario. Why no surprise? On the one hand, Bosch noted that "there have been few studies to demonstrate an effect of blood pressure-lowering on cognitive decline." At the same time, "there have not been [any] studies to show a protective effect" linked to statins, with some prior research having raised "concerns, based on observational data, that statins [may even] cause memory loss," she added. On the bright side, "results actually confirm that there is no greater cognitive decline in those taking statin compared to placebo," Bosch said. "So, no effect is actually reassuring in this case." Worldwide, roughly 1 in 10 individuals over the age of 60 suffer from some degree of thinking impairment, the investigators noted. Prior research has suggested that living with uncontrolled high blood pressure and/or high cholesterol during middle age may raise the long-term risk for developing thinking declines. Still, research has been mixed as to whether that risk can be limited by taking drugs to control heart disease risk factors. In the latest study, published online Feb. 27 in the journal Neurology, the participants were an average age of 74, while 6 in 10 were women. Just under half (45 percent) had high blood pressure, and all were believed to face a moderate risk for developing heart disease. Health via WebMD Health https://www.webmd.com/ February 28, 2019 at 12:40PM
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